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Anti-PA2G4 Polyclonal Antibody
Cat: K003953P
Summary:
【Product name】:Anti-PA2G4 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5036 【Swiss Prot】:Q9UQ80
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:500-2000.IHC 1:50-200
【Immunogen】:Recombinant protein of human PA2G4
【Public Immunogen Range】:1-394aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.
Verified picture:
Western blot analysis with PA2G4 antibody diluted at 1:1000;Lane: Mouse liver BxPC-3 HeLa PC-12 NIH3T3 K-562 22Rv1 HT-29.
Immunohistochemistry of paraffin-embedded rat heart using PA2G4 antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded rat lung with PA2G4 antibody diluted at 1:100.