Anti-CHMP2B Polyclonal Antibody
Cat: K003968P
Summary:
| 【Product name】：Anti-CHMP2B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：25978 | 【Swiss Prot】：Q9UQN3 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：Recombinant protein of human CHMP2B | |
| 【Public Immunogen Range】：1-213aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Verified picture:
Immunohistochemistry of paraffin-embedded gastric cancer(hu) using CHMP2B antibody at dilution of 1:100 (x40 lens).
Western blot analysis with CHMP2B antibody diluted at 1:1000;Lane: MCF7 BT-474 22Rv1 Lovo A549 Mouse lung Mouse testis Mouse kidney.