Anti-CUL4B Polyclonal Antibody
Cat: K003969P
Summary:
| 【Product name】：Anti-CUL4B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8450 | 【Swiss Prot】：Q13620 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human CUL4B | |
| 【Public Immunogen Range】：1-200aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded rat liver using CUL4B antibody at dilution of 1:200.
Western blot analysis with CUL4B antibody diluted at 1:1000;Lane: Mouse liver Mouse kidney.
Immunofluorescence analysis of U2OS cells using CUL4B antibody diluted at 1:100.