Anti-RIPK3 Polyclonal Antibody
Cat: K003990P
Summary:
| 【Product name】：Anti-RIPK3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：11035 | 【Swiss Prot】：Q9Y572 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human RIPK3 | |
| 【Public Immunogen Range】：21-287aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Verified picture:
Western blot analysis with RIPK3 antibody diluted at 1:1000;Lane:HT-29
Immunohistochemistry of paraffin-embedded Human liver cancer with RIPK3 antibody diluted at 1:100
Immunofluorescence analysis of C6 cells using RIPK3 antibody diluted at 1:100