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Anti-RFC4 Polyclonal Antibody - SAlexa Fluor 680
Cat: K004030P - SAlexa Fluor 680
Summary:
【Product name】:Anti-RFC4 Polyclonal Antibody - SAlexa Fluor 680 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5984 【Swiss Prot】:P35249
【Tested applications】:IP,IF,WB
【Recommended dilution】:WB 1:500-2000. IF 1:50-100. IP 0.5μg-4μg.
【Immunogen】:Recombinant protein of human RFC4
【Public Immunogen Range】:204-363aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
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