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Anti-RNF2 Polyclonal Antibody
Cat: K004067P
Summary:
【Product name】:Anti-RNF2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:6045 【Swiss Prot】:Q99496
【Tested applications】:IHC,WB,IP,ChIP,IF
【Recommended dilution】:WB 1:100-500. IHC 1:50-200. IF 1:50-200. IP 0.5μg-4μg. ChIP 5μg.
【Immunogen】:Recombinant protein of human RNF2
【Public Immunogen Range】:1-336aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Verified picture:
Western blot analysis with RNF2 antibody diluted at 1:1000;Lane: Jurkat.
Immunohistochemistry of paraffin-embedded rat lung using RNF2 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human liver cancer with RNF2 antibody diluted at 1:100.