Anti-QDPR Polyclonal Antibody
Cat: K004170P
Summary:
| 【Product name】：Anti-QDPR Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5860 | 【Swiss Prot】：P09417 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000 | |
| 【Immunogen】：Recombinant protein of human QDPR | |
| 【Public Immunogen Range】：1-244aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
Verified picture:
Western blot analysis with QDPR antibody diluted at 1:1000;Lane: Mouse liver Mouse kidney Mouse brain Rat liver.