Anti-PEX5 Polyclonal Antibody
Cat: K004208P
Summary:
| 【Product name】：Anti-PEX5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5830 | 【Swiss Prot】：P50542 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human PEX5 | |
| 【Public Immunogen Range】：1-260aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The peroxisomal targeting signal type1 (PTS1) receptor, PEX5, is one member of peroxins (PEXs) which are proteins required for peroxisome assembly. PEX5 and PEX7 function as receptors that recognize PTS1- and PTS2- containing proteins, respectively, and PEX5 binds PTS1 through its C-terminal 40-kDa tetratricopeptide repeat domain. It is a predominantly cytoplasmic, partly peroxisomal protein that appears to shuttle between these compartments as it mediates the import of PTS1-containing proteins. PEX5 has been reported to interact with PEX10, PEX12, PEX13, and PEX14. Defects in PEX5 are a cause of Zellweger syndrome (ZWS), which is a lethal peroxisome biogenesis disorder. This antibody recognizes endogenous PEX5, which migrates with an apparent molecular mass of 80 kDa (PMID: 7790377).
Verified picture:
Immunohistochemistry of paraffin-embedded human liver injury using PEX5 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with PEX5 antibody diluted at 1:1000;Lane: SW480 ES-2 293T HepG2 MCF7 HeLa Mouse liver Mouse kidney Mouse uterus.
Immunohistochemistry of paraffin-embedded human liver damage with PEX5 antibody diluted at 1:100.
Immunofluorescence analysis of HeLa cells using PEX5 antibody diluted at 1:100.