Anti-NTRK3 Polyclonal Antibody
Cat: K004248P
Summary:
| 【Product name】：Anti-NTRK3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4916 | 【Swiss Prot】：Q16288 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:500-2000.IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human NTRK3 | |
| 【Public Immunogen Range】：40-300aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with NTRK3 antibody diluted at 1:1000;Lane: A549 BT-474 HepG2 Mouse brain MCF7 Mouse liver.
Immunofluorescence analysis of rat brain cells using NTRK3 antibody diluted at 1:100.