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Anti-SP100 Polyclonal Antibody
Cat: K004256P
Summary:
【Product name】:Anti-SP100 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:6672 【Swiss Prot】:P23497
【Tested applications】:WB
【Recommended dilution】:WB 1:500-2000.
【Immunogen】:Recombinant protein of human SP100
【Public Immunogen Range】:181-480aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
Verified picture:
Western blot analysis with SP100 antibody diluted at 1:1000;Lane: MCF7 HeLa 293T HepG2 Mouse spleen Mouse thymus Mouse lung Mouse heart Mouse liver.