Anti-FUS Polyclonal Antibody
Cat: K004300P
Summary:
| 【Product name】：Anti-FUS Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2521 | 【Swiss Prot】：P35637 |
| 【Tested applications】：IP,IF,WB | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:50-100. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human FUS | |
| 【Public Immunogen Range】：297-526aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
Verified picture:
Western blot analysis with FUS antibody diluted at 1:1000;Lane: 293T.
Immunohistochemistry of paraffin-embedded Rat brain with FUS antibody diluted at 1:100
Immunofluorescence analysis of C6 cells using FUS antibody diluted at 1:100