下载
Anti-GSK3B Polyclonal Antibody
Cat: K004355P
Summary:
【Product name】:Anti-GSK3B Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:2932 【Swiss Prot】:P49841
【Tested applications】:WB,IP,IF
【Recommended dilution】:WB 1:500-1000. IP 0.5μg-4μg. IF 1:50-200.
【Immunogen】:A synthetic peptide of human GSK3B
【Public Immunogen Range】:320-420aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Colorectal cancer(hu) using GSK3B antibody at dilution of 1:100 (x100 lens,x200 lens).
Western blot analysis with GSK3B antibody diluted at 1:700;Lane: LO2 HeLa 22Rv1 U-251MG.