Anti-SET Polyclonal Antibody - SAlexa Fluor 405
Cat: K004367P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-SET Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6418 | 【Swiss Prot】：Q01105 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:100-500. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SET | |
| 【Public Immunogen Range】：1-277aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
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