Anti-NEU1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K004418P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-NEU1 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4758 | 【Swiss Prot】：Q99519 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human NEU1 | |
| 【Public Immunogen Range】：210-415aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
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