Anti-RCC1 Polyclonal Antibody
Cat: K004452P
Summary:
| 【Product name】：Anti-RCC1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1104 | 【Swiss Prot】：P18754 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:1000-2000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human RCC1 | |
| 【Public Immunogen Range】：1-240aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.
Verified picture:
Western blot analysis with RCC1 antibody diluted at 1:1500;Lane: U-87MG MCF7 HeLa SW620 LO2.
Immunohistochemistry of paraffin-embedded human breast cancer with RCC1 antibody diluted at 1:100.
Immunofluorescence analysis of HeLa cells using RCC1 antibody diluted at 1:100.