Anti-RCC1 Polyclonal Antibody - SAlexa Fluor 633
Cat: K004452P - SAlexa Fluor 633
Summary:
| 【Product name】：Anti-RCC1 Polyclonal Antibody - SAlexa Fluor 633 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1104 | 【Swiss Prot】：P18754 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:1000-2000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human RCC1 | |
| 【Public Immunogen Range】：1-240aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.
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