下载
Anti-CLPS Polyclonal Antibody
Cat: K004462P
Summary:
【Product name】:Anti-CLPS Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1208 【Swiss Prot】:P04118
【Tested applications】:WB
【Recommended dilution】:WB 1:500-2000
【Immunogen】:Recombinant protein of human CLPS
【Public Immunogen Range】:18-112aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded liver cancer��hu�� using CLPS antibody at dilution of 1:100 (x100 lens,x200 lens).
Western blot analysis with CLPS antibody diluted at 1:1000;Lane: Mouse pancreas.