Anti-PAICS Polyclonal Antibody
Cat: K004539P
Summary:
| 【Product name】：Anti-PAICS Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10606 | 【Swiss Prot】：P22234 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-2000.IF 1:10-100 | |
| 【Immunogen】：Recombinant protein of human PAICS | |
| 【Public Immunogen Range】：176-425aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunofluorescence analysis of U2OS cell using PAICS antibody. Blue: DAPI for nuclear staining.
Western blot analysis with PAICS antibody diluted at 1:1000;Lane: Jurkat 293T SW620 Raji HeLa.