Anti-PRAME Polyclonal Antibody - SAlexa Fluor 660
Cat: K004543P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-PRAME Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23532 | 【Swiss Prot】：P78395 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-2000. IF1:20-50. | |
| 【Immunogen】：Recombinant protein of human PRAME | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues except testis. The encoded protein acts as a repressor of retinoic acid receptor and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
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