Anti-HAO1 Polyclonal Antibody
Cat: K004555P
Summary:
| 【Product name】：Anti-HAO1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：54363 | 【Swiss Prot】：Q9UJM8 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-200.IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human HAO1 | |
| 【Public Immunogen Range】：1-370aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
Verified picture:
Immunohistochemistry of paraffin-embedded human liver cancer using HAO1 antibody at dilution of 1:200 (x40 lens).
Western blot analysis with HAO1 antibody diluted at 1:1000;Lane: Mouse liver Rat liver.
Immunofluorescence analysis of rat liver cells using HAO1 antibody diluted at 1:100.