Anti-AGPAT2 Polyclonal Antibody
Cat: K004578P
Summary:
| 【Product name】：Anti-AGPAT2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10555 | 【Swiss Prot】：O15120 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:50-100. | |
| 【Immunogen】：Recombinant protein of human AGPAT2 | |
| 【Public Immunogen Range】：199-278aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Verified picture:
Immunofluorescence analysis of HeLa cell using AGPAT2 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with AGPAT2 antibody diluted at 1:1000;Lane: HT-29.