Anti-CCT4 Polyclonal Antibody
Cat: K004605P
Summary:
| 【Product name】：Anti-CCT4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10575 | 【Swiss Prot】：P50991 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:100-500. | |
| 【Immunogen】：Recombinant protein of human CCT4 | |
| 【Public Immunogen Range】：130-390aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
Verified picture:
Immunofluorescence analysis of HeLa cell using CCT4 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with CCT4 antibody diluted at 1:1000;Lane: MCF7 THP-1 Mouse spleen.