Anti-CD207 Polyclonal Antibody
Cat: K004609P
Summary:
| 【Product name】：Anti-CD207 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：50489 | 【Swiss Prot】：Q9UJ71 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-1000. | |
| 【Immunogen】：Recombinant protein of human CD207 | |
| 【Public Immunogen Range】：70-200aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Verified picture:
Western blot analysis with CD207 antibody diluted at 1:1000;Lane: A549 A431 Jurkat Mouse lung Rat lung Rat liver.