下载
Anti-CREB3 Polyclonal Antibody
Cat: K004621P
Summary:
【Product name】:Anti-CREB3 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:10488 【Swiss Prot】:O43889
【Tested applications】:IF,WB
【Recommended dilution】:WB 1:500-2000.IF 1:10-100
【Immunogen】:Recombinant protein of human CREB3
【Public Immunogen Range】:1-230aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.
Verified picture:
Immunofluorescence analysis of HeLa cell using CREB3 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with CREB3 antibody diluted at 1:1000;Lane: Jurkat HeLa 293T HepG2 Mouse brain Mouse liver Mouse pancreas.
Immunofluorescence analysis of C6 cells using CREB3 antibody diluted at 1:50.