Anti-POLG2 Polyclonal Antibody
Cat: K004719P
Summary:
| 【Product name】：Anti-POLG2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：11232 | 【Swiss Prot】：Q9UHN1 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:10-100. | |
| 【Immunogen】：Recombinant protein of human POLG2 | |
| 【Public Immunogen Range】：216-485aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
Verified picture:
Western blot analysis with POLG2 antibody diluted at 1:1000;Lane: 293T MCF7.
Immunohistochemistry of paraffin-embedded rat heart tissue using POLG2 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of MCF7 cells using POLG2 antibody diluted at 1:50.