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Anti-TRAF3IP2 Polyclonal Antibody
Cat: K004788P
Summary:
【Product name】:Anti-TRAF3IP2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:10758 【Swiss Prot】:O43734
【Tested applications】:IF,WB
【Recommended dilution】:WB 1:500-1000. IF 1:50-200.
【Immunogen】:Recombinant protein of human TRAF3IP2
【Public Immunogen Range】:1-300aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Verified picture:
Western blot analysis with TRAF3IP2 antibody diluted at 1:1000;Lane: Mouse lung Mouse heart.
Immunofluorescence analysis of NIH3T3 cells using TRAF3IP2 antibody diluted at 1:100.