Anti-PDE5A Polyclonal Antibody
Cat: K004813P
Summary:
| 【Product name】：Anti-PDE5A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8654 | 【Swiss Prot】：O76074 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：Recombinant protein of human PDE5A | |
| 【Public Immunogen Range】：1-150aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Verified picture:
Western blot analysis with PDE5A antibody diluted at 1:1000;Lane: HT-1080 SKOV3 A549 22Rv1 Mouse brain Mouse skeletal muscle Rat skeletal muscle.