Anti-MAP2K5 Polyclonal Antibody
Cat: K004891P
Summary:
| 【Product name】：Anti-MAP2K5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5607 | 【Swiss Prot】：Q13163 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:50-100. | |
| 【Immunogen】：Recombinant protein of human MAP2K5 | |
| 【Public Immunogen Range】：1-190aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Verified picture:
Immunohistochemistry of paraffin-embedded liver cancer(hu) using MAP2K5 antibody at dilution of 1:100 (x100 lens,x200 lens).
Immunofluorescence analysis of U2OS cell using MAP2K5 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with MAP2K5 antibody diluted at 1:1000;Lane: NCI-H460 BT-474 Mouse liver Rat liver Rat kidney.
Immunohistochemistry of paraffin-embedded rat heart with MAP2K5 antibody diluted at 1:100.
Immunofluorescence analysis of MCF7 cells using MAP2K5 antibody diluted at 1:100.