Anti-SGCD Polyclonal Antibody
Cat: K004912P
Summary:
| 【Product name】：Anti-SGCD Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6444 | 【Swiss Prot】：Q92629 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-100. | |
| 【Immunogen】：Recombinant protein of human SGCD | |
| 【Public Immunogen Range】：61-290aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Verified picture:
Western blot analysis with SGCD antibody diluted at 1:1000;Lane: Jurkat THP-1 Mouse heart Mouse skeletal muscle Rat heart Rat skeletal muscle.
Immunohistochemistry of paraffin-embedded rat heart using SGCD antibody at dilution of 1:100 (x40 lens).