Anti-TNNI3 Polyclonal Antibody
Cat: K004924P
Summary:
| 【Product name】：Anti-TNNI3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7137 | 【Swiss Prot】：P19429 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human TNNI3 | |
| 【Public Immunogen Range】：1-100aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Verified picture:
Western blot analysis with TNNI3 antibody diluted at 1:1000
Immunofluorescence analysis of mouse heart cells using TNNI3 antibody diluted at 1:100.