下载
Anti-TNNI3 Polyclonal Antibody - SAlexa Fluor 660
Cat: K004924P - SAlexa Fluor 660
Summary:
【Product name】:Anti-TNNI3 Polyclonal Antibody - SAlexa Fluor 660 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:7137 【Swiss Prot】:P19429
【Tested applications】:IF,WB
【Recommended dilution】:WB 1:500-2000. IF 1:50-200
【Immunogen】:Recombinant protein of human TNNI3
【Public Immunogen Range】:1-100aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Verified picture: