Anti-PIAS3 Polyclonal Antibody
Cat: K004979P
Summary:
| 【Product name】：Anti-PIAS3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10401 | 【Swiss Prot】：Q9Y6X2 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000.IHC 1:50-100. | |
| 【Immunogen】：Recombinant protein of human PIAS3 | |
| 【Public Immunogen Range】：452-628aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.
Verified picture:
Western blot analysis with PIAS3 antibody diluted at 1:1000;Lane: Mouse brain Rat kidney Rat brain Rat lung.
Immunohistochemistry of paraffin-embedded rat brain using PIAS3 antibody at dilution of 1:100 (x40 lens).