Anti-COPS6 Polyclonal Antibody
Cat: K004988P
Summary:
| 【Product name】：Anti-COPS6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10980 | 【Swiss Prot】：Q7L5N1 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:100-500. IF 1:50-100. | |
| 【Immunogen】：Recombinant protein of human COPS6 | |
| 【Public Immunogen Range】：58-327aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Verified picture:
Western blot analysis with COPS6 antibody diluted at 1:1000;Lane: MCF7 Mouse brain Rat testis.
Immunofluorescence analysis of A549 cell using COPS6 antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of MCF7 cells using COPS6 antibody diluted at 1:100.