Anti-HDAC7 Polyclonal Antibody
Cat: K005138P
Summary:
| 【Product name】：Anti-HDAC7 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51564 | 【Swiss Prot】：Q8WUI4 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:50-100. | |
| 【Immunogen】：A synthetic peptide of human HDAC7 | |
| 【Public Immunogen Range】：400-500aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunofluorescence analysis of A549 cell using HDAC7 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with HDAC7 antibody diluted at 1:1000;Lane: NIH3T3 A549 MCF7.
Immunofluorescence analysis of MCF7 cells using HDAC7 antibody diluted at 1:100.