Anti-PAX6 Polyclonal Antibody
Cat: K005181P
Summary:
| 【Product name】：Anti-PAX6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5080 | 【Swiss Prot】：P26367 |
| 【Tested applications】：IF,WB,IP | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human PAX6 | |
| 【Public Immunogen Range】：1-300aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with PAX6 antibody diluted at 1:1000;Lane: Mouse brain Rat brain.
Immunofluorescence analysis of A549 cell using PAX6 antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using PAX6 antibody diluted at 1:100.