Anti-ETFA Polyclonal Antibody
Cat: K005383P
Summary:
| 【Product name】：Anti-ETFA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2108 | 【Swiss Prot】：P13804 |
| 【Tested applications】：IP,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human ETFA | |
| 【Public Immunogen Range】：1-333aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with ETFA antibody diluted at 1:1000;Lane: MCF7 A549 SW620 HepG2 Mouse liver Mouse kidney Mouse heart Rat liver.
Immunohistochemistry of paraffin-embedded liver cancer(hu) using ETFA antibody at dilution of 1:100 (x100 lensx,200 lens).
Immunohistochemistry of paraffin-embedded rat brain with ETFA antibody diluted at 1:100.