Anti-LOX Polyclonal Antibody
Cat: K005397P
Summary:
| 【Product name】：Anti-LOX Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4015 | 【Swiss Prot】：P28300 |
| 【Tested applications】：IHC,WB,IF | |
| 【Recommended dilution】：WB 1:100-500. IHC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human LOX | |
| 【Public Immunogen Range】：300-400aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections.
Verified picture:
Western blot analysis with LOX antibody diluted at 1:1000
Immunofluorescence analysis of BALB-3T3 cells using LOX antibody diluted at 1:100.