Anti-SHMT1 Polyclonal Antibody
Cat: K005419P
Summary:
| 【Product name】：Anti-SHMT1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6470 | 【Swiss Prot】：P34896 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SHMT1 | |
| 【Public Immunogen Range】：285-444aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded human stomach using SHMT1 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with SHMT1 antibody diluted at 1:1000;Lane: Mouse liver Rat liver Rat kidney.