Anti-PLOD1 Polyclonal Antibody
Cat: K005553P
Summary:
| 【Product name】：Anti-PLOD1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5351 | 【Swiss Prot】：Q02809 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-1000. | |
| 【Immunogen】：Recombinant protein of human PLOD1 | |
| 【Public Immunogen Range】：19-295aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with PLOD1 antibody diluted at 1:1000;Lane: HepG2 A431 U-251MG Mouse kidney Mouse heart.