Anti-IRS2 Polyclonal Antibody
Cat: K005574P
Summary:
| 【Product name】：Anti-IRS2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8660 | 【Swiss Prot】：Q9Y4H2 |
| 【Tested applications】：IHC,WB,IF | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human IRS2 | |
| 【Public Immunogen Range】：1238-1338aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Verified picture:
Western blot analysis with IRS2 antibody diluted at 1:1000;Lane: HT-29 K-562 Mouse kidney Rat kidney.
Immunofluorescence analysis of NIH3T3 cells using IRS2 antibody diluted at 1:100.