Anti-POR Polyclonal Antibody
Cat: K005679P
Summary:
| 【Product name】：Anti-POR Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5447 | 【Swiss Prot】：P16435 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-100.IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human POR | |
| 【Public Immunogen Range】：1-250aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Verified picture:
Western blot analysis with POR antibody diluted at 1:1000;Lane: A549 HeLa MCF7 293T Mouse liver Mouse skin Mouse kidney Rat brain.
Immunohistochemistry of paraffin-embedded human esophagus using POR antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of C6 cells using POR antibody diluted at 1:100.