Anti-LLGL2 Polyclonal Antibody
Cat: K005737P
Summary:
| 【Product name】：Anti-LLGL2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：217325 | 【Swiss Prot】：Q3TJ91 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-2000.IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of mouse LLGL2 | |
| 【Public Immunogen Range】：620-819aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with LLGL2 antibody diluted at 1:1000;Lane: MCF7 Mouse liver Rat liver.
Immunofluorescence analysis of U2OS cells using LLGL2 antibody diluted at 1:100.