Anti-CD163 Polyclonal Antibody
Cat: K005801P
Summary:
| 【Product name】：Anti-CD163 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9332 | 【Swiss Prot】：Q86VB7 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000.IHC 1:50-200.IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CD163 | |
| 【Public Immunogen Range】：750-1050aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Verified picture:
Western blot analysis with CD163 antibody diluted at 1:700;Lane: Mouse heart Mouse thymus Rat liver.
Immunohistochemistry of paraffin-embedded human colon carcinoma with CD163 antibody diluted at 1:100.
Immunofluorescence analysis of THP-1 cells using CD163 antibody diluted at 1:100.