Anti-DSG3 Polyclonal Antibody
Cat: K005817P
Summary:
| 【Product name】：Anti-DSG3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1830 | 【Swiss Prot】：P32926 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:100-500. | |
| 【Immunogen】：Recombinant protein of human DSG3 | |
| 【Public Immunogen Range】：749-999aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
Verified picture:
Immunohistochemistry of paraffin-embedded Skin cancer(hu) using DSG3 antibody at dilution of 1:100 (x100 lens,x200 lens).
Western blot analysis with DSG3 antibody diluted at 1:1000;Lane: A431.