Anti-GBA Polyclonal Antibody
Cat: K005822P
Summary:
| 【Product name】：Anti-GBA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2629 | 【Swiss Prot】：P04062 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human GBA | |
| 【Public Immunogen Range】：40-250aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using GBA antibody at dilution of 1:100 (x100 lens,x200 lens).
Western blot analysis with GBA antibody diluted at 1:1000;Lane: MCF7.