Anti-NEFH Polyclonal Antibody
Cat: K005841P
Summary:
| 【Product name】：Anti-NEFH Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4744 | 【Swiss Prot】：P12036 |
| 【Tested applications】：IP,IF,WB | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human NEFH | |
| 【Public Immunogen Range】：873-1020aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
Verified picture:
Western blot analysis with NEFH antibody diluted at 1:1000;Lane: Mouse brain Mouse liver Rat brain Rat liver.
Immunofluorescence analysis of C6 cells using NEFH antibody diluted at 1:100.