Anti-COL6A1 Polyclonal Antibody
Cat: K006016P
Summary:
| 【Product name】：Anti-COL6A1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1291 | 【Swiss Prot】：P12109 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000 | |
| 【Immunogen】：Recombinant protein of human COL6A1 | |
| 【Public Immunogen Range】：19-250aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Verified picture:
Western blot analysis with COL6A1 antibody diluted at 1:1000;Lane: SKOV3,HepG2,HT-1080,Mouse heart,Mouse lung,Mouse pancreas
Immunohistochemistry of paraffin-embedded human lung cancer with COL6A1 antibody diluted at 1:100