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Anti-NUMB Polyclonal Antibody
Cat: K006027P
Summary:
【Product name】:Anti-NUMB Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:8650 【Swiss Prot】:P49757
【Tested applications】:IF,IHC,WB
【Recommended dilution】:WB 1:500-1000. IHC 1:50-200. IF 1:50-200.
【Immunogen】:Recombinant protein of human NUMB
【Public Immunogen Range】:521-640aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with NUMB antibody diluted at 1:1000;Lane: HeLa NIH3T3 SH-SY5Y.
Immunohistochemistry of paraffin-embedded human liver with NUMB antibody diluted at 1:100.
Immunofluorescence analysis of NIH3T3 cells using NUMB antibody diluted at 1:100.