Anti-IMPDH1 Polyclonal Antibody
Cat: K006035P
Summary:
| 【Product name】：Anti-IMPDH1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3614 | 【Swiss Prot】：P20839 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:1000-2000.IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human IMPDH1 | |
| 【Public Immunogen Range】：434-563aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with IMPDH1 antibody diluted at 1:1500;Lane: NIH3T3 293T BT-474.
Immunofluorescence analysis of L929 cells using IMPDH1 antibody diluted at 1:100.