Anti-GLDC Polyclonal Antibody - Cy7
Cat: K006116P - Cy7
Summary:
| 【Product name】：Anti-GLDC Polyclonal Antibody - Cy7 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2731 | 【Swiss Prot】：P23378 |
| 【Tested applications】：IP,IF,WB | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:50-100. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human GLDC | |
| 【Public Immunogen Range】：36-290aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
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